Little has changed in the landscape surrounding Brandywine Manor House Inn since the time when its first residents lived here. James and Jane Mackelduff were part of the 1722 Scots/Irish migration from Maryland and Delaware into southern Pennsylvania. They established a large and successful 1,210-acre plantation along the West Branch of the Brandywine Creek. They built one of the first, if not the first, grist and saw mills in the area and continued milling into the 19th century. Their son, Samuel, converted the original log house into the current 2-½-story dwelling in 1740. As the first home on the plantation it was named The Manor House. The Mackelduff family was very influential in the community. Having a sincere belief in God, they were instrumental in founding the nearby Forks of the Brandywine Presbyterian Church. The grave of James Mackelduff, is the earliest known Mackelduff burial (1760) at the Forks of the Brandywine Presbyterian Church cemetery. The house remained in the Mackelduff family until the early 1900's. Dr. and Mrs. Gordon Eck purchased the farm in 1983. During the next twenty years, the house was restored and several additions added to accommodate their seven children.

The character of this circa 1740 home is warm and friendly with deep windowsills, nine fireplaces (three walk-in), winding staircases, polished random width floors, and authentic beautiful antiques. Whether you choose a room such as The Aberdeen or The Longwood, or a suite such as The Richmond or The Williamsburg, your stay is sure to be delightful. Each room boasts a king or queen-sized bed, spacious private bath, cable TV, and Internet access.